Research Articles
ALDEx2 vs ANCOM-BC: A Comprehensive Guide for Choosing the Right Differential Abundance Tool in Microbiome Research
This guide provides a detailed, current comparison of two prominent tools for differential abundance analysis in microbiome datasets: ALDEx2 and ANCOM-BC.
ALDEx2 for Mixed Population RNA-seq Analysis: A Comprehensive Guide for Accurate Differential Expression
This guide provides a comprehensive overview of ALDEx2, a powerful tool designed specifically for differential abundance analysis in RNA-seq datasets derived from mixed populations, such as microbiomes or heterogeneous tissues.
ALDEx2 Differential Abundance Analysis: A Complete Guide for Biomedical Researchers
This comprehensive guide explores ALDEx2 (ANOVA-Like Differential Expression 2), a robust biostatistical tool for differential abundance analysis in high-throughput sequencing data like microbiome 16S rRNA and metatranscriptomics.
16S vs. ITS rRNA Sequencing: Choosing the Right Tool for Microbial Profiling
This article provides a comprehensive comparative analysis of 16S and ITS ribosomal RNA gene sequencing, the cornerstone techniques for bacterial/fungal microbiome analysis.
Primer Bias in 16S rRNA Sequencing: Comprehensive Correction Methods for Accurate Microbiome Analysis
This article provides a comprehensive guide to primer bias in 16S rRNA gene sequencing, a critical challenge for researchers and drug development professionals seeking accurate microbiome characterization.
16S rRNA vs Shotgun Metagenomics: Choosing the Right Microbiome Profiling Method for Biomedical Research
This comprehensive guide compares 16S rRNA gene sequencing and shotgun metagenomics, the two dominant approaches for microbiome analysis.
16S rRNA vs. Metagenomics: A Beginner's Guide for Biomedical Researchers Choosing Microbial Profiling Methods
This article provides a foundational and applied comparison of 16S rRNA gene sequencing and shotgun metagenomics for researchers entering the field of microbiome analysis.
A Complete 16S rRNA Sequencing Protocol for Gut Microbiome Analysis: From Sample to Insights for Biomedical Research
This comprehensive guide details a modern 16S rRNA gene sequencing protocol optimized for gut microbiome studies, tailored for researchers and drug development professionals.
16S rRNA Sequencing in Clinical Diagnostics: A Comprehensive Guide for Researchers and Drug Developers
This article provides a detailed exploration of 16S rRNA gene sequencing as a transformative tool for bacterial infection diagnostics.
The Complete Guide to 16S rRNA Primer Selection: Optimizing Coverage for Specific Bacterial Groups in Research
This comprehensive guide addresses the critical challenge of 16S rRNA gene primer selection for researchers, scientists, and drug development professionals.